Would you shy away from listing cards on Ebay that will end over Labor Day weekend?

Just wondering if anyone has any experience putting cards up on ebay that end on a holiday weekend...like Labor Day weekend. Are there a lot less people bidding?
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Buying Vintage, all sports.
Buying Woody Hayes, Les Horvath, Vic Janowicz, and Jesse Owens autographed items
Always looking for Topps Salesman Samples, pre '51 unopened packs, E90-2, E91a, N690 Kalamazoo Bats, and T204 Square Frame Ramly's
(Edited to fix typo.)
Vintage Football Card Gallery